Abstract
We report a spectroscopic technique that combines the Fourier-Transform Infrared Spectroscopy with the Surface Plasmon Resonance. This tool enables sensitive infrared spectroscopy of liquid and solid objects in the attenuated total reflectance mode. The FTIR-SPR technique is similar to FTIR-ATR technique but has higher sensitivity due to resonance amplification of the surface electric field. The label-free FTIR-SPR technique is especially advantageous for living cell studies since it combines spectroscopic information inherent to FTIR with structural information provided by the Surface Plasmon Resonance. We discuss the FTIR-SPR technique for label-free studies of cell sedimentation and spreading on substrate and for surface plasmon spectroscopy.
Original language | English |
---|---|
Title of host publication | Plasmons |
Subtitle of host publication | Theory and Applications |
Publisher | Nova Science Publishers, Inc. |
Pages | 327-343 |
Number of pages | 17 |
ISBN (Electronic) | 9781617614217 |
State | Published - 11 Feb 2021 |
Bibliographical note
Publisher Copyright:© 2011 by Nova Science Publishers, Inc.
Keywords
- Biosensor
- Cell culture
- FTIR
- Infrared
- Surface plasmon