Inhibition of pp60(c-Src) reduces Bcl-X(L) expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

Keyphrases

• Human Epidermal Growth Factor Receptor 2 (HER2) 100%
• Overexpressing 100%
• C-Src 100%
• Transformed Phenotype 100%
• Bcl-xL 100%
• Src Kinase 66%
• Tumor 50%
• Bcl-x 50%
• Src Kinase Inhibitor 33%
• Tyrosine Phosphorylation 16%
• Cancer Types 16%
• Luciferase Reporter Gene 16%
• Anticancer Agents 16%
• Signaling Molecules 16%
• Dominant Negative 16%
• EGFR Signaling 16%
• Cell Death 16%
• Growth Arrest 16%
• Apoptotic Pathway 16%
• Mitogenic Signaling 16%
• Antisense RNA 16%
• Programmed Cell Death 16%
• Negative Type 16%
• Induced Expression 16%
• Oncogenic Activity 16%
• EGFR Family 16%
• Signaling Elements 16%
• Oncogenic Phenotype 16%
• Malignancy Grade 16%
• Anti-apoptotic 16%
• Kinase-dead 16%
• EGFR Receptor 16%

Neuroscience

• Epidermal Growth Factor Receptor 100%
• Oncogene Src 100%
• Epidermal Growth Factor Receptor 2 100%
• Kinase 83%
• Cell Death 33%
• Promoter Region 33%
• Protein Phosphorylation 16%
• Receptor Tyrosine Kinase 16%
• Cell Line 16%
• Carcinogenesis 16%
• Antisense RNA 16%
• Luciferase 16%
• Reporter Gene 16%
• Growth Disorder 16%
• Anticarcinogen 16%
• Receptor 16%
• Oncogenic activity 16%