Inhibitory effect of oxidized spermine on the multiplication of coliphage T5

U. Bachrach*, J. Leibovici

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

T5 phages, treated with oxidized spermine, adsorb to bacterial cells and inject their DNA along with oxidized spermine. The injected phage DNA does not replicate and does not give rise to a complementary RNA. On the other hand, bacterial DNA and the respective complementary RNA are synthesized after infection with treated phages. The findings have been interpreted by assuming the formation of a biologically inactive complex between phage DNA and oxidized spermine.

Original languageEnglish
Pages (from-to)120-132
Number of pages13
JournalJournal of Molecular Biology
Volume19
Issue number1
DOIs
StatePublished - 1966

Keywords

  • MAK
  • mRNA
  • messenger RNA
  • methylated albumin-kieselguhr
  • p.f.u.
  • plaque-forming units

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