Abstract
The three papers reviewed here report data that show Ini1 plays an essential role in murine development; Inil-null embryos die between 3.5 and 5.5 days post fertilization. Additionally, Ini1 functions as a tumor suppressor in the murine model. Ini1-heterozygous mice present with a range of tumors with variable penetrance.
Original language | English |
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Pages (from-to) | 751-756 |
Number of pages | 6 |
Journal | Chemtracts |
Volume | 14 |
Issue number | 13 |
State | Published - 2001 |
Externally published | Yes |