Ini1 is essential for embryonic development and tumor suppression

Cynthia J. Guidi; Stephen N. Jones; Anthony N. Imbalzano; C. J. Guidi; A. T. Sands; B. P. Zambrowicz; T. K. Turner; D. A. Demers; W. Webster; T. W. Smith; A. N. Imbalzano; S. N. Jones; A. Klochendler-Yeivin; L. Fiette; J. Barra; C. Muchardt; C. Babinet; M. Yaniv; C. W.M. Roberts; S. A. Galusha; M. E. McMenamin; C. D.M. Fletcher; S. H. Orkin

Ini1 is essential for embryonic development and tumor suppression

Cynthia J. Guidi^*
, Stephen N. Jones
, Anthony N. Imbalzano
, C. J. Guidi^*
, A. T. Sands
, B. P. Zambrowicz
, T. K. Turner
, D. A. Demers
, W. Webster
, T. W. Smith
, A. N. Imbalzano
, S. N. Jones
, A. Klochendler-Yeivin
, L. Fiette
, J. Barra
, C. Muchardt
, C. Babinet
, M. Yaniv
, C. W.M. Roberts
, S. A. Galusha

M. E. McMenamin, C. D.M. Fletcher, S. H. Orkin

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

The three papers reviewed here report data that show Ini1 plays an essential role in murine development; Inil-null embryos die between 3.5 and 5.5 days post fertilization. Additionally, Ini1 functions as a tumor suppressor in the murine model. Ini1-heterozygous mice present with a range of tumors with variable penetrance.

Original language	English
Pages (from-to)	751-756
Number of pages	6
Journal	Chemtracts
Volume	14
Issue number	13
State	Published - 2001
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

Guidi, C. J., Jones, S. N., Imbalzano, A. N., Guidi, C. J., Sands, A. T., Zambrowicz, B. P., Turner, T. K., Demers, D. A., Webster, W., Smith, T. W., Imbalzano, A. N., Jones, S. N., Klochendler-Yeivin, A., Fiette, L., Barra, J., Muchardt, C., Babinet, C., Yaniv, M., Roberts, C. W. M., ... Orkin, S. H. (2001). Ini1 is essential for embryonic development and tumor suppression. Chemtracts, 14(13), 751-756.

@article{7a5cc419977f42ceb72df53a8758ee2f,

title = "Ini1 is essential for embryonic development and tumor suppression",

abstract = "The three papers reviewed here report data that show Ini1 plays an essential role in murine development; Inil-null embryos die between 3.5 and 5.5 days post fertilization. Additionally, Ini1 functions as a tumor suppressor in the murine model. Ini1-heterozygous mice present with a range of tumors with variable penetrance.",

author = "Guidi, \{Cynthia J.\} and Jones, \{Stephen N.\} and Imbalzano, \{Anthony N.\} and Guidi, \{C. J.\} and Sands, \{A. T.\} and Zambrowicz, \{B. P.\} and Turner, \{T. K.\} and Demers, \{D. A.\} and W. Webster and Smith, \{T. W.\} and Imbalzano, \{A. N.\} and Jones, \{S. N.\} and A. Klochendler-Yeivin and L. Fiette and J. Barra and C. Muchardt and C. Babinet and M. Yaniv and Roberts, \{C. W.M.\} and Galusha, \{S. A.\} and McMenamin, \{M. E.\} and Fletcher, \{C. D.M.\} and Orkin, \{S. H.\}",

year = "2001",

language = "אנגלית",

volume = "14",

pages = "751--756",

journal = "Chemtracts",

issn = "1431-9268",

publisher = "Data Trace Publishing Co.",

number = "13",

}

Guidi, CJ, Jones, SN, Imbalzano, AN, Guidi, CJ, Sands, AT, Zambrowicz, BP, Turner, TK, Demers, DA, Webster, W, Smith, TW, Imbalzano, AN, Jones, SN, Klochendler-Yeivin, A, Fiette, L, Barra, J, Muchardt, C, Babinet, C, Yaniv, M, Roberts, CWM, Galusha, SA, McMenamin, ME, Fletcher, CDM & Orkin, SH 2001, 'Ini1 is essential for embryonic development and tumor suppression', Chemtracts, vol. 14, no. 13, pp. 751-756.

TY - JOUR

T1 - Ini1 is essential for embryonic development and tumor suppression

AU - Guidi, Cynthia J.

AU - Jones, Stephen N.

AU - Imbalzano, Anthony N.

AU - Guidi, C. J.

AU - Sands, A. T.

AU - Zambrowicz, B. P.

AU - Turner, T. K.

AU - Demers, D. A.

AU - Webster, W.

AU - Smith, T. W.

AU - Imbalzano, A. N.

AU - Jones, S. N.

AU - Klochendler-Yeivin, A.

AU - Fiette, L.

AU - Barra, J.

AU - Muchardt, C.

AU - Babinet, C.

AU - Yaniv, M.

AU - Roberts, C. W.M.

AU - Galusha, S. A.

AU - McMenamin, M. E.

AU - Fletcher, C. D.M.

AU - Orkin, S. H.

PY - 2001

Y1 - 2001

N2 - The three papers reviewed here report data that show Ini1 plays an essential role in murine development; Inil-null embryos die between 3.5 and 5.5 days post fertilization. Additionally, Ini1 functions as a tumor suppressor in the murine model. Ini1-heterozygous mice present with a range of tumors with variable penetrance.

AB - The three papers reviewed here report data that show Ini1 plays an essential role in murine development; Inil-null embryos die between 3.5 and 5.5 days post fertilization. Additionally, Ini1 functions as a tumor suppressor in the murine model. Ini1-heterozygous mice present with a range of tumors with variable penetrance.

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AN - SCOPUS:0035716942

SN - 1431-9268

VL - 14

SP - 751

EP - 756

JO - Chemtracts

JF - Chemtracts

IS - 13

ER -

Ini1 is essential for embryonic development and tumor suppression

Abstract

UN SDGs

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