Interethnic differences in drug response: The contribution of genetic variability in β adrenergic receptor and cytochrome P4502C9

M. Muszkat*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Ethnic differences in drug response have been extensively reported, and ethnicity has been suggested to be useful clinically as a predictor of drug response. Genetic polymorphisms in the genes encoding β1 adrenergic receptor (AR) and β2 AR, targets of β AR antagonists, and in cytochrome P4502C9, the enzyme involved in warfarin metabolism, have the potential to explain some of the observed ethnic variability in drug response and to improve clinical practice.

Original languageAmerican English
Pages (from-to)215-218
Number of pages4
JournalClinical Pharmacology and Therapeutics
Volume82
Issue number2
DOIs
StatePublished - Aug 2007

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