Interleukin-4: production by mast cell lines and by non-B, non-T cells

S. Z. Ben-Sasson; G. le Gros; M. Plaut; D. Conrad; F. D. Finkelman; W. E. Paul

Interleukin-4: production by mast cell lines and by non-B, non-T cells

S. Z. Ben-Sasson, G. le Gros, M. Plaut, D. Conrad, F. D. Finkelman, W. E. Paul

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

A short section in this chapter discusses the effect of Nippostrongylus brasiliensis infection on the interleukin 4 (IL-4) producing capacity of non-B, non-T cells in BALB/c mice. The infected mice show large increases (∼300 fold) in serum IgE levels, which are completely blocked by treatment with anti-IL4 antibody. There is a large increase in the percentage of spleen cells in the non-B, non-T compartment (up to 25%), marked increases in the IL4 producing capacity of the non-B, non-T cells (∼50 fold) and increased spleen sizes (∼2 fold).

Original language	English
Title of host publication	Molecular aspects of immune response and infectious diseases
Editors	H. Kiyono, E. Jirillo, C. De Simone
Place of Publication	New York
Publisher	Raven Press
Pages	11–18
Volume	1
ISBN (Print)	0-88167-686-1
State	Published - 1990

Publication series

Name	Advances in Host Defense Mechanisms
Volume	1

Bibliographical note

CABI Record Number: 19910874288

Access to Document

https://www.cabidigitallibrary.org/doi/full/10.5555/19910874288

Cite this

Ben-Sasson, S. Z., Gros, G. L., Plaut, M., Conrad, D., Finkelman, F. D., & Paul, W. E. (1990). Interleukin-4: production by mast cell lines and by non-B, non-T cells. In H. Kiyono, E. Jirillo, & C. De Simone (Eds.), Molecular aspects of immune response and infectious diseases (Vol. 1, pp. 11–18). ( Advances in Host Defense Mechanisms; Vol. 1). Raven Press. https://www.cabidigitallibrary.org/doi/full/10.5555/19910874288

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title = "Interleukin-4: production by mast cell lines and by non-B, non-T cells",

abstract = "A short section in this chapter discusses the effect of Nippostrongylus brasiliensis infection on the interleukin 4 (IL-4) producing capacity of non-B, non-T cells in BALB/c mice. The infected mice show large increases (∼300 fold) in serum IgE levels, which are completely blocked by treatment with anti-IL4 antibody. There is a large increase in the percentage of spleen cells in the non-B, non-T compartment (up to 25\%), marked increases in the IL4 producing capacity of the non-B, non-T cells (∼50 fold) and increased spleen sizes (∼2 fold).",

author = "Ben-Sasson, \{S. Z.\} and Gros, \{G. le\} and M. Plaut and D. Conrad and Finkelman, \{F. D.\} and Paul, \{W. E.\}",

note = "CABI Record Number: 19910874288 ",

year = "1990",

language = "אנגלית",

isbn = "0-88167-686-1",

volume = "1",

series = " Advances in Host Defense Mechanisms",

publisher = "Raven Press",

pages = "11–18",

editor = "H. Kiyono and \{ Jirillo\}, E. and \{De Simone\}, C.",

booktitle = "Molecular aspects of immune response and infectious diseases",

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}

Ben-Sasson, SZ, Gros, GL, Plaut, M, Conrad, D, Finkelman, FD & Paul, WE 1990, Interleukin-4: production by mast cell lines and by non-B, non-T cells. in H Kiyono, E Jirillo & C De Simone (eds), Molecular aspects of immune response and infectious diseases. vol. 1, Advances in Host Defense Mechanisms, vol. 1, Raven Press, New York, pp. 11–18. <https://www.cabidigitallibrary.org/doi/full/10.5555/19910874288>

Interleukin-4: production by mast cell lines and by non-B, non-T cells. / Ben-Sasson, S. Z.; Gros, G. le; Plaut, M. et al.
Molecular aspects of immune response and infectious diseases. ed. / H. Kiyono; E. Jirillo; C. De Simone. Vol. 1 New York: Raven Press, 1990. p. 11–18 ( Advances in Host Defense Mechanisms; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - Interleukin-4

T2 - production by mast cell lines and by non-B, non-T cells

AU - Ben-Sasson, S. Z.

AU - Gros, G. le

AU - Plaut, M.

AU - Conrad, D.

AU - Finkelman, F. D.

AU - Paul, W. E.

N1 - CABI Record Number: 19910874288

PY - 1990

Y1 - 1990

N2 - A short section in this chapter discusses the effect of Nippostrongylus brasiliensis infection on the interleukin 4 (IL-4) producing capacity of non-B, non-T cells in BALB/c mice. The infected mice show large increases (∼300 fold) in serum IgE levels, which are completely blocked by treatment with anti-IL4 antibody. There is a large increase in the percentage of spleen cells in the non-B, non-T compartment (up to 25%), marked increases in the IL4 producing capacity of the non-B, non-T cells (∼50 fold) and increased spleen sizes (∼2 fold).

AB - A short section in this chapter discusses the effect of Nippostrongylus brasiliensis infection on the interleukin 4 (IL-4) producing capacity of non-B, non-T cells in BALB/c mice. The infected mice show large increases (∼300 fold) in serum IgE levels, which are completely blocked by treatment with anti-IL4 antibody. There is a large increase in the percentage of spleen cells in the non-B, non-T compartment (up to 25%), marked increases in the IL4 producing capacity of the non-B, non-T cells (∼50 fold) and increased spleen sizes (∼2 fold).

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SN - 0-88167-686-1

VL - 1

T3 - Advances in Host Defense Mechanisms

SP - 11

EP - 18

BT - Molecular aspects of immune response and infectious diseases

A2 - Kiyono, H.

A2 - Jirillo, E.

A2 - De Simone, C.

PB - Raven Press

CY - New York

ER -

Interleukin-4: production by mast cell lines and by non-B, non-T cells

Abstract

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