Intraventricular glucose administration inhibits feeding in satiated but not in 24 hours food deprived cocks

Injection of 5 μl isotonic glucose into the third ventricle above the basal hypothalamus but not in the posterior hypothalamus-anterior midbrain, suppressed feeding in satiated cocks. This suppression of food intake was less dramatic when glucose was injected after 5 hr of food deprivation and was eliminated if 24 hr of food deprivation preceded the glucose administration. An involvement of a glucostatic mechanism in the regulation of feeding in the chicken is suggested.