Intrinsic control of electroresponsive properties of transplanted mammalian brain neurons

Jørn Hounsgaard*, Yosef Yarom

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The present study presents the first analysis of neurons in mammalian brain transplants based on intracellular recording. The results, obtained in brain slices including both donor and host tissue, showed that neuronal precursor cells in embryonic transplantsretained their ability to complete their normal differentiation of cell-type-specific electroresponsive properties. Distortions in cell aggregation and synaptic connectivity did not affect this aspect of neuronal differentiation.

Original languageEnglish
Pages (from-to)372-376
Number of pages5
JournalBrain Research
Volume335
Issue number2
DOIs
StatePublished - 3 Jun 1985

Keywords

  • brain transplant
  • cerebellum
  • electroresponsive property
  • hippocampus
  • intracellular recording

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