Invasive group A streptococcal infections, Israel

Allon E. Moses*, Sara Goldberg, Zinaida Korenman, Miriam Ravins, Emanuel Hanski, Mervyn Shapiro

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

We conducted a prospective, nationwide, population-based study of invasive group A streptococcal infections in Israel. We identified 409 patients (median age 27 years; range <1-92), for an annual incidence of 3.7/100,000 (11/100,000 in Jerusalem). The mortality rate was 5%. Bacteremia occurred in 125 cases (31%). The most common illnesses were soft-tissue infection (63%) and primary bacteremia (14%). Thirty percent of patients had no identifiable risk factors for infection. Eighty-seven percent of pharyngeal carriers had the same serotype as the index patient. M types included M3 (25%), M28 (10%), and M-nontypable (33%). A marked paucity of M1 serotype (1.2%) was detected. The results highlighted concentrated pockets of invasive disease in the Jewish orthodox community (annual incidence 16/100,000).

Original languageEnglish
Pages (from-to)421-426
Number of pages6
JournalEmerging Infectious Diseases
Volume8
Issue number4
DOIs
StatePublished - 2002

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