Abstract
Field desorption (FD) mass spectrometry was applied to the determination of prostaglandin E2 (PGE2) in urine. Studies on synthetic compounds showed that methyl esters are stable under FD mass spectrometric conditions. The ester of PGE2 gives rise to protonated molecular ions and fragments due to the elimination of water and the side chains C8H14O and C8H12O2. This behaviour enabled its determination in the nanogram per millilitre range.
Original language | English |
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Pages (from-to) | 427-430 |
Number of pages | 4 |
Journal | Biological Mass Spectrometry |
Volume | 16 |
Issue number | 1-12 |
DOIs | |
State | Published - Oct 1988 |