TY - JOUR
T1 - Investigation of molecular motion and interprotein interactions in solutions by TDDS
T2 - a comparison with NMR data
AU - Ermolina, Irina
AU - Fedotov, Vladimir
AU - Feldman, Yuri
AU - Ivoylov, Igor
PY - 1994/9/1
Y1 - 1994/9/1
N2 - The results of dynamic protein behavior in solution studied by time domain dielectric spectroscopy (TDDS) are presented. The analyses for myoglobin solutions at concentrations 50, 120 and 150 mg/ml in the temperature interval from 5 to 35°C was carried out in terms of dipole correlation functions. It was found that the correlation function of the protein motion can be presented as a sum of three components corresponding to three types of protein motion: internal local motion, anisotropy rotational Brownian diffusion and translational Brownian diffusion. According to the hypothesis presented earlier, it is supposed that the reason for anisotropy of protein rotation and capability for the detection translational diffusion (slowest motion) is the mutual interprotein electrostatic steering.
AB - The results of dynamic protein behavior in solution studied by time domain dielectric spectroscopy (TDDS) are presented. The analyses for myoglobin solutions at concentrations 50, 120 and 150 mg/ml in the temperature interval from 5 to 35°C was carried out in terms of dipole correlation functions. It was found that the correlation function of the protein motion can be presented as a sum of three components corresponding to three types of protein motion: internal local motion, anisotropy rotational Brownian diffusion and translational Brownian diffusion. According to the hypothesis presented earlier, it is supposed that the reason for anisotropy of protein rotation and capability for the detection translational diffusion (slowest motion) is the mutual interprotein electrostatic steering.
UR - http://www.scopus.com/inward/record.url?scp=0028494965&partnerID=8YFLogxK
U2 - 10.1016/0022-3093(94)90629-7
DO - 10.1016/0022-3093(94)90629-7
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AN - SCOPUS:0028494965
SN - 0022-3093
VL - 172-174
SP - 1103
EP - 1108
JO - Journal of Non-Crystalline Solids
JF - Journal of Non-Crystalline Solids
IS - PART 2
ER -