IPF1/PDX1 Deficiency and β-Cell Dysfunction in Psammomys obesus, an Animal with Type 2 Diabetes

Keyphrases

• Basal Level 20%
• Cell Dysfunction 100%
• Diabetes 20%
• DNA Binding 40%
• Efficient Expression 20%
• Elevated Glucose 20%
• Gene Products 20%
• Gene Transfer 20%
• Glucose Concentration 20%
• Glucose Transporter 2 (GLUT2) 20%
• High Glucose 20%
• High-calorie Diet 40%
• Homeodomain Transcription Factor 20%
• Hyperglycemia 20%
• Immunostaining 20%
• Insulin 40%
• Insulin Content 40%
• Insulin Gene Expression 40%
• Insulin mRNA 20%
• Insulin Transcription Factor 20%
• ISL1 20%
• Islet 100%
• MRNA Level 20%
• Nkx2.1 20%
• Nkx6.1 20%
• Pdx1 100%
• Polymerase Chain Reaction Analysis 20%
• Prohormone Convertase 1/3 20%
• Psammomys Obesus 100%
• Quantitative PCR 20%
• Transcription Factor 20%
• Type 2 Diabetes Mellitus (T2DM) 100%
• Western Blot 20%

Biochemistry, Genetics and Molecular Biology

• Animal Model 33%
• Binding Affinity 33%
• DNA Binding 66%
• Furin 33%
• Gene Expression 66%
• Gene Product 33%
• Glucose Transporter 33%
• Homeodomain 33%
• Hyperglycemia 33%
• Immunostaining 33%
• Messenger RNA 33%
• PDX1 100%
• Psammomys obesus 100%
• Reverse Transcription Polymerase Chain Reaction 33%
• Transcription Factor MafA 33%
• Transcription Factors 66%
• Western Blotting 33%