Abstract
A sensitive assay was used to compare the biological activity of cord serum erythropoietin in two groups of infants born with or without labor-induced hypoxia. The mean cord serum erythropoietin activity in 161 infants delivered after vaginal labor was 116 +/- 36 mU/mL, and was indistinguishable from that observed in 23 infants delivered by preplanned, elective cesarean section, 114 +/- 12 mU/mL (P = .75). The bioassay measured effective erythropoietin activity, including the contribution of potentiators in serum. These results indicate that duration and intensity of labor are insufficient to cause a significant increase in effective erythropoietin activity.
Original language | English |
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Pages (from-to) | 215-219 |
Number of pages | 5 |
Journal | Journal of Perinatology |
Volume | 12 |
Issue number | 3 |
State | Published - Sep 1992 |
Externally published | Yes |