ISSCR standards for the use of human stem cells in basic research

Tenneille E. Ludwig*, Peter W. Andrews, Ivana Barbaric, Nissim Benvenisty, Anita Bhattacharyya, Jeremy M. Crook, Laurence M. Daheron, Jonathan S. Draper, Lyn E. Healy, Meritxell Huch, Maneesha S. Inamdar, Kim B. Jensen, Andreas Kurtz, Madeline A. Lancaster, Prisca Liberali, Matthias P. Lutolf, Christine L. Mummery, Martin F. Pera, Yoji Sato, Noriko ShimasakiAustin G. Smith, Jihwan Song, Claudia Spits, Glyn Stacey, Christine A. Wells, Tongbiao Zhao, Jack T. Mosher

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaningful, and durable, standards that ensure reproducibility and reliability of the data should be applied. Although such standards have been previously proposed for repositories and distribution centers, no widely accepted best practices exist for laboratory research with human pluripotent and tissue stem cells. To fill that void, the International Society for Stem Cell Research has developed a set of recommendations, including reporting criteria, for scientists in basic research laboratories. These criteria are designed to be technically and financially feasible and, when implemented, enhance the reproducibility and rigor of stem cell research.

Original languageAmerican English
Pages (from-to)1744-1752
Number of pages9
JournalStem Cell Reports
Issue number9
StatePublished - 12 Sep 2023

Bibliographical note

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  • hESCS
  • hIPSCs
  • human
  • model systems
  • organoids
  • tissue stem cells


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