Knowledge-based structure prediction of MHC class I bound peptides: A study of 23 complexes

Keyphrases

• Side Chain 100%
• MHC Class I 100%
• Knowledge Base 100%
• Structure Prediction 100%
• Rotamer Library 60%
• Peptide Backbone 40%
• Peptide-MHC Complex 40%
• Prediction Quality 40%
• T Cells 20%
• Antigenic Peptide 20%
• Binding Peptide 20%
• MHC Molecules 20%
• Immunogenicity 20%
• Energy Function 20%
• Buried Residues 20%
• Rational Design 20%
• Protein Sequence 20%
• Structural Information 20%
• Per Se 20%
• Proposed Methodology 20%
• Predictive Algorithm 20%
• Peptide Structure 20%
• Peptide Sequencing 20%
• Peptide-based 20%
• Peptide Binding 20%
• Negligible Effects 20%
• Backbone Structure 20%
• Accurate Modeling 20%
• Side-chain Conformation 20%
• Rotamers 20%
• Dead-time Elimination 20%
• Peptide Vaccine 20%
• Modeling Algorithm 20%
• MHC Binding 20%
• Fast Modeling 20%

Biochemistry, Genetics and Molecular Biology

• Peptide Sequence 100%
• MHC Class I 100%
• Structure Prediction 100%
• T Cell 50%
• Protein Structure 50%
• Conformation 50%
• DNA Template 50%
• Immunogenicity 50%
• Vaccine Peptide 50%

Chemistry

• Rotamer 100%
• Amino Acid Sequence 50%
• antigenic 25%