Koninginin b: A Biologically Active Congener of Koninginin a from Trichoderma Koningii

Horace G. Cutler*, David S. Himmelsbach, John M. Jacyno, Patsy D. Cole, Boris Yagen, Richard F. Arrendale, Richard H. Cox

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Koninginin B, a biologically active natural product related to koninginin A, was isolated from Tri-choderma koningii, an organism isolated from the roots and soil line of a Diffenbachia sp. The compound, which inhibited the growth of etiolated wheat coleoptiles 100 % at 10−3 M, was a white, finely crystalline compound with molecular formula C16H26O4 and a melting point of 72-74 °C. The structure was established as 8-hydroxy-2-(l-hydroxyheptyl)-3,4,5,6,7,8-hexahydro-2H-1-benzopyran-5-one by comparison with koninginin A, UV, IR, 1H NMR, 13C NMR, and MS.

Original languageEnglish
Pages (from-to)977-980
Number of pages4
JournalJournal of Agricultural and Food Chemistry
Volume39
Issue number5
DOIs
StatePublished - 1 May 1991

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