TY - JOUR
T1 - Left Ventricular Mass as a Risk Factor in the Oldest Old
AU - Bursztyn, Michael
AU - Leibowitz, David
AU - Stessman-Lande, Irit
AU - Jacobs, Jeremy M.
AU - Ein-Mor, Eliana
AU - Stessman, Jochanan
N1 - Publisher Copyright:
© 2015 Wiley Periodicals, Inc.
PY - 2015/11
Y1 - 2015/11
N2 - In middle-aged and "young elderly" cohorts, higher left ventricular mass (LVM) is associated with worse outcomes. The authors examined LVM and 5-year mortality among community-dwelling 85-year-old patients. A representative sample (n=526, born 1920-1921) from the Jerusalem Longitudinal Cohort Study underwent echocardiography at age 85. LVM was indexed by body surface area (LVM-BSA) or height (LVM-Ht). Patients with higher LVM were less educated and sedentary and had poorer self-rated health, functional limitations, and increased comorbidity. Five-year mortality was 21.7% (n=114). Adjusted 5-year mortality rates were increased for the two upper quintiles of LVM-BSA (hazard ratio [HR], 1.8; 95% confidence interval [CI], 1.05-3.06) and LVM-Ht (HR, 2.2; 95% CI, 1.2-3.5). A step up in mortality occurred around the third quintile corresponding with LVM-BSA 110 g/m2 or LVM-Ht 51 g/m2.7. Among the oldest old, elevated LVM is significantly associated with mortality.
AB - In middle-aged and "young elderly" cohorts, higher left ventricular mass (LVM) is associated with worse outcomes. The authors examined LVM and 5-year mortality among community-dwelling 85-year-old patients. A representative sample (n=526, born 1920-1921) from the Jerusalem Longitudinal Cohort Study underwent echocardiography at age 85. LVM was indexed by body surface area (LVM-BSA) or height (LVM-Ht). Patients with higher LVM were less educated and sedentary and had poorer self-rated health, functional limitations, and increased comorbidity. Five-year mortality was 21.7% (n=114). Adjusted 5-year mortality rates were increased for the two upper quintiles of LVM-BSA (hazard ratio [HR], 1.8; 95% confidence interval [CI], 1.05-3.06) and LVM-Ht (HR, 2.2; 95% CI, 1.2-3.5). A step up in mortality occurred around the third quintile corresponding with LVM-BSA 110 g/m2 or LVM-Ht 51 g/m2.7. Among the oldest old, elevated LVM is significantly associated with mortality.
UR - http://www.scopus.com/inward/record.url?scp=84945494748&partnerID=8YFLogxK
U2 - 10.1111/jch.12594
DO - 10.1111/jch.12594
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C2 - 26075863
AN - SCOPUS:84945494748
SN - 1524-6175
VL - 17
SP - 874
EP - 879
JO - Journal of Clinical Hypertension
JF - Journal of Clinical Hypertension
IS - 11
ER -