Abstract
Leishmaniasis caused by Leishmania infantum is an important zoonotic disease transmitted by sand flies with a high prevalence of infection in dogs and cats in regions whereby transmission occurs. Clinical disease is systemic with variable presenting signs and degrees of severity. It affects the skin, lymph nodes, eyes, bone marrow, kidneys, and other organs. The clinical findings in dogs and cats with L. infantum infection are generally similar. Subclinical infection of canines and felines in endemic areas is frequent. Long-term treatment of the disease with allopurinol, or combination of allopurinol with meglumine antimoniate or miltefosine, is needed, and clinical relapse is probable.
| Original language | English |
|---|---|
| Pages (from-to) | 1359-1375 |
| Number of pages | 17 |
| Journal | Veterinary Clinics of North America - Small Animal Practice |
| Volume | 52 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 2022 |
Bibliographical note
Funding Information:The authors declare that they have no conflict of interest related to any of the topics presented in this publication.
Keywords
- Allopurinol
- Canine leishmaniasis
- Co-infection
- Feline leishmaniasis
- Leishmania infantum
- Meglumine antimoniate
- Miltefosine
- Topical insecticides