Lensless fiber endomicroscopy in biomedicine

Jiawei Sun, Robert Kuschmierz, Ori Katz, Nektarios Koukourakis, Juergen W. Czarske*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Lensless fiber endomicroscopy, an emergent paradigm shift for minimally-invasive microscopic optical imaging and targeted light delivery, holds transformative potential, especially in biomedicine. Leveraging holographic detection and physical or computational wavefront correction, it enables three-dimensional imaging in an unprecedentedly small footprint, which is crucial for various applications such as brain surgery. This perspective reviews the recent breakthroughs, highlighting potential emerging applications, and pinpointing gaps between innovation and real-world applications. As the research in this realm accelerates, the novel breakthroughs and existing frontiers highlighted in this perspective can be used as guidelines for researchers joining this exciting domain.

Original languageAmerican English
Article number18
Issue number1
StatePublished - Dec 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024.


  • Biomedical imaging
  • Lensless endomicroscope
  • Multicore fibers
  • Multimode fibers
  • Translation to real-world applications


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