Lipid Nano-Vehicles Based On Lyotropic Liquid Crystals As Drug Delivery Vehicles

Dima Libster*, Abraham Aserin, Nissim Garti

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

This chapter demonstrates that Liquid Crystals (LC) mesophases with complex architectures were rationally designed and prepared for the solubilization and potential administration of bioactive molecules. It shows that comprehensive understanding of the structural properties of the carriers is imperative for rational and successful tailoring of delivery vehicles. The principal strategy was to first characterize the different levels of organization of these special materials and then to explore the detailed relationships and possible correlations between them, their structures, and the macroscopic properties. The results lately obtained, although very interesting and promising, definitely do not cover all the aspects and do not answer all the questions addressed by the fascinating field of lyotropic liquid crystals and their applications as drug delivery systems. Clearly, many additional experiments need to be carried out to clarify the detailed structure, the exact properties, and the specific potential of these systems. However, the chapter looks forward to open a new window and provide new thoughts and interest into this rapidly growing field of research.

Original languageEnglish
Title of host publicationLipids in Nanotechnology
PublisherElsevier Inc.
Pages191-219
Number of pages29
ISBN (Electronic)9780128043455
ISBN (Print)9780981893679
DOIs
StatePublished - 2012

Bibliographical note

Publisher Copyright:
© 2012 AOCS Press Published by Elsevier Inc. All rights reserved.

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