TY - GEN
T1 - Liver metastasis early detection using fMRI based statistical model
AU - Freiman, Moti
AU - Edrei, Yifat
AU - Gross, Eitan
AU - Joskowicz, Leo
AU - Abramovitch, Rinat
PY - 2008
Y1 - 2008
N2 - We present a novel method for computer aided early detection of liver metastases. The method used fMRI-based statistical modeling to characterize colorectal hepatic metastases and follow their early hemodynamical changes. Changes in hepatic hemodynamics were evaluated from T2*-W fMRI images acquired during the breathing of air, air-CO2, and carbogen. A classification model was built to differentiate between metastatic and healthy liver tissue. The model was constructed from 128 validated fMRI samples of metastatic and healthy mice liver tissue using histogram-based features and SVM classification engine. The model was subsequently tested with a set of 32 early, non-validated fMRI samples. Our model yielded an accuracy of 84.38% with 80% precision.
AB - We present a novel method for computer aided early detection of liver metastases. The method used fMRI-based statistical modeling to characterize colorectal hepatic metastases and follow their early hemodynamical changes. Changes in hepatic hemodynamics were evaluated from T2*-W fMRI images acquired during the breathing of air, air-CO2, and carbogen. A classification model was built to differentiate between metastatic and healthy liver tissue. The model was constructed from 128 validated fMRI samples of metastatic and healthy mice liver tissue using histogram-based features and SVM classification engine. The model was subsequently tested with a set of 32 early, non-validated fMRI samples. Our model yielded an accuracy of 84.38% with 80% precision.
KW - Computer-aided diagnosis
KW - Early detection
KW - Liver metastasis
KW - Statistical analysis
KW - fMRI analysis
UR - http://www.scopus.com/inward/record.url?scp=51049122583&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2008.4541063
DO - 10.1109/ISBI.2008.4541063
M3 - ???researchoutput.researchoutputtypes.contributiontobookanthology.conference???
AN - SCOPUS:51049122583
SN - 9781424420032
T3 - 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI
SP - 584
EP - 587
BT - 2008 5th IEEE International Symposium on Biomedical Imaging
T2 - 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
Y2 - 14 May 2008 through 17 May 2008
ER -