Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly

M. Muszkat; G. Friedman; M. H. Schein; P. Naveh; E. Greenbaum; M. Schlesinger; Z. Zakay-Rones; A. Ben Yehuda

doi:10.1016/S0264-410X(99)00509-5

Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly

M. Muszkat, G. Friedman, M. H. Schein, P. Naveh, E. Greenbaum, M. Schlesinger, Z. Zakay-Rones, A. Ben Yehuda

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Community-residing elderly were immunized twice intranasally three weeks apart with a new inactivated whole influenza vaccine. A control group was immunized intramuscularly with conventional influenza vaccine. Local antibody response was detected in about 50% of intranasally immunized subjects compared to about 20% of intramuscularly immunized subjects, to the three viral strains. Increasing the incidence of elevated IgA response may prevent influenza at its early stages thus reducing complications in the elderly. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	1696-1699
Number of pages	4
Journal	Vaccine
Volume	18
Issue number	16
DOIs	https://doi.org/10.1016/S0264-410X(99)00509-5
State	Published - 25 Feb 2000

Keywords

Elderly
Inactive influenza vaccine
Intranasal immunization

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0264-410X(99)00509-5

Cite this

@article{b0ca45ffb7254b4c9a21a90c32f7ee6a,

title = "Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly",

abstract = "Community-residing elderly were immunized twice intranasally three weeks apart with a new inactivated whole influenza vaccine. A control group was immunized intramuscularly with conventional influenza vaccine. Local antibody response was detected in about 50% of intranasally immunized subjects compared to about 20% of intramuscularly immunized subjects, to the three viral strains. Increasing the incidence of elevated IgA response may prevent influenza at its early stages thus reducing complications in the elderly. (C) 2000 Elsevier Science Ltd.",

keywords = "Elderly, Inactive influenza vaccine, Intranasal immunization",

author = "M. Muszkat and G. Friedman and Schein, {M. H.} and P. Naveh and E. Greenbaum and M. Schlesinger and Z. Zakay-Rones and Yehuda, {A. Ben}",

year = "2000",

month = feb,

day = "25",

doi = "10.1016/S0264-410X(99)00509-5",

language = "אנגלית",

volume = "18",

pages = "1696--1699",

journal = "Vaccine",

issn = "0264-410X",

publisher = "Elsevier Ltd.",

number = "16",

}

TY - JOUR

T1 - Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly

AU - Muszkat, M.

AU - Friedman, G.

AU - Schein, M. H.

AU - Naveh, P.

AU - Greenbaum, E.

AU - Schlesinger, M.

AU - Zakay-Rones, Z.

AU - Yehuda, A. Ben

PY - 2000/2/25

Y1 - 2000/2/25

N2 - Community-residing elderly were immunized twice intranasally three weeks apart with a new inactivated whole influenza vaccine. A control group was immunized intramuscularly with conventional influenza vaccine. Local antibody response was detected in about 50% of intranasally immunized subjects compared to about 20% of intramuscularly immunized subjects, to the three viral strains. Increasing the incidence of elevated IgA response may prevent influenza at its early stages thus reducing complications in the elderly. (C) 2000 Elsevier Science Ltd.

AB - Community-residing elderly were immunized twice intranasally three weeks apart with a new inactivated whole influenza vaccine. A control group was immunized intramuscularly with conventional influenza vaccine. Local antibody response was detected in about 50% of intranasally immunized subjects compared to about 20% of intramuscularly immunized subjects, to the three viral strains. Increasing the incidence of elevated IgA response may prevent influenza at its early stages thus reducing complications in the elderly. (C) 2000 Elsevier Science Ltd.

KW - Elderly

KW - Inactive influenza vaccine

KW - Intranasal immunization

UR - http://www.scopus.com/inward/record.url?scp=0033951397&partnerID=8YFLogxK

U2 - 10.1016/S0264-410X(99)00509-5

DO - 10.1016/S0264-410X(99)00509-5

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 10689151

AN - SCOPUS:0033951397

SN - 0264-410X

VL - 18

SP - 1696

EP - 1699

JO - Vaccine

JF - Vaccine

IS - 16

ER -

Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this