TY - JOUR
T1 - Localization of mRNA and axis formation during Xenopus embryogenesis.
AU - Melton, D. A.
AU - Ruiz i Altaba, A.
AU - Yisraeli, J.
AU - Sokol, S.
PY - 1989
Y1 - 1989
N2 - This paper summarizes our recent work concerned with the developmental polarity of the frog egg and the patterning of the embryonic body plan. In two separate projects, we are studying genes involved in setting up basic embryonic axes. One of these genes, Vg1, codes for a maternal mRNA that is localized in the frog egg. The Vg1 gene is used in studies on the induction of mesoderm and as a probe to understand how the polarity of an egg is established. A second gene, Xhox3, contains a homeodomain and is differentially expressed in the axial mesoderm. Our studies suggest that this homeobox gene is critically involved in setting up different positional values along the anteroposterior axis.
AB - This paper summarizes our recent work concerned with the developmental polarity of the frog egg and the patterning of the embryonic body plan. In two separate projects, we are studying genes involved in setting up basic embryonic axes. One of these genes, Vg1, codes for a maternal mRNA that is localized in the frog egg. The Vg1 gene is used in studies on the induction of mesoderm and as a probe to understand how the polarity of an egg is established. A second gene, Xhox3, contains a homeodomain and is differentially expressed in the axial mesoderm. Our studies suggest that this homeobox gene is critically involved in setting up different positional values along the anteroposterior axis.
UR - http://www.scopus.com/inward/record.url?scp=0024367543&partnerID=8YFLogxK
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C2 - 2673675
AN - SCOPUS:0024367543
SN - 0300-5208
VL - 144
SP - 16-29; discussion 29-2936, 92-98
JO - Ciba Foundation symposium
JF - Ciba Foundation symposium
ER -