Localization, quantification, and characterization of tuftelin in soft tissues

Yoav Leiser, Anat Blumenfeld, Amir Haze, Leah Dafni, Angela L. Taylor, Eli Rosenfeld, Eran Fermon, Yael Gruenbaum-Cohen, Boaz Shay, Dan Deutsch*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Tuftelin was initially found in the developing and mature extracellular enamel. Here we describe our novel discovery of tuftelin cellular distribution (protein and mRNA) in six soft tissues. The expression levels of tuftelin mRNA were significantly higher in mouse kidney and testis, in which oxygen levels are hovering closely to hypoxia under normal conditions.

Original languageEnglish
Pages (from-to)449-454
Number of pages6
JournalAnatomical Record
Volume290
Issue number5
DOIs
StatePublished - May 2007

Keywords

  • Expression
  • Hypoxia
  • Immunohistochemistry
  • In situ hybridization
  • Quantification
  • Soft tissues
  • Tuftelin

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