Long, monomolecular guanine-based nanowires

Alexander B. Kotlyar*, Natalia Borovok, Tatiana Molotsky, Hezy Cohen, Errez Shapir, Danny Porath

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

122 Scopus citations


The synthesis and characterization of continuous monomolecular G-wires, made of guanine tetrads, composed of single, self-folded poly(G) strands of thousands of bases were carried out. The cation-independent wires were characterized using gel electrophoresis, UV spectroscopy, circular dichroism (CD) spectroscopy, and atomic force microscopy (AFM). The G-wires showed high stability and resistance to heat treatment. The wires were utterly insensitive and resistant to DNase that efficiently degrades native DNA.

Original languageAmerican English
Pages (from-to)1901-1905
Number of pages5
JournalAdvanced Materials
Issue number15
StatePublished - 4 Aug 2005


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