Lutzomyia longipalpis is a species complex: Genetic divergence and interspecific hybrid sterility among three populations

G. C. Lanzaro; K. Ostrovska; M. V. Herrero; P. G. Lawyer; A. Warburg

doi:10.4269/ajtmh.1993.48.839

Lutzomyia longipalpis is a species complex: Genetic divergence and interspecific hybrid sterility among three populations

G. C. Lanzaro^*, K. Ostrovska, M. V. Herrero, P. G. Lawyer, A. Warburg

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

125 Scopus citations

Abstract

The sand fly Lutzomyia longipalpis is the vector of Leishmania donovani chagasi in Latin America. An analysis of genetic variability at 27 enzyme coding loci among three laboratory populations of Lu. longipalpis revealed substantial genetic polymorphism. Levels of genetic distance between all pairwise comparisons of colonies were very high, and consistent with those previously reported among separate species in the genus Lutzomyia. Between 7% and 22% of the loci studied were diagnostic for any two of the colony populations. Experimental hybridization between colonies resulted in the production of sexually sterile male progeny. Our results provide strong evidence that Lu. longipalpis exists in nature as a complex of at least three distinct species. The possible effects of colonization on the genetic makeup of laboratory populations is considered in extending our results to natural populations.

Original language	American English
Pages (from-to)	839-847
Number of pages	9
Journal	American Journal of Tropical Medicine and Hygiene
Volume	48
Issue number	6
DOIs	https://doi.org/10.4269/ajtmh.1993.48.839
State	Published - 1993
Externally published	Yes

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title = "Lutzomyia longipalpis is a species complex: Genetic divergence and interspecific hybrid sterility among three populations",

abstract = "The sand fly Lutzomyia longipalpis is the vector of Leishmania donovani chagasi in Latin America. An analysis of genetic variability at 27 enzyme coding loci among three laboratory populations of Lu. longipalpis revealed substantial genetic polymorphism. Levels of genetic distance between all pairwise comparisons of colonies were very high, and consistent with those previously reported among separate species in the genus Lutzomyia. Between 7% and 22% of the loci studied were diagnostic for any two of the colony populations. Experimental hybridization between colonies resulted in the production of sexually sterile male progeny. Our results provide strong evidence that Lu. longipalpis exists in nature as a complex of at least three distinct species. The possible effects of colonization on the genetic makeup of laboratory populations is considered in extending our results to natural populations.",

author = "Lanzaro, {G. C.} and K. Ostrovska and Herrero, {M. V.} and Lawyer, {P. G.} and A. Warburg",

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T1 - Lutzomyia longipalpis is a species complex

T2 - Genetic divergence and interspecific hybrid sterility among three populations

AU - Lanzaro, G. C.

AU - Ostrovska, K.

AU - Herrero, M. V.

AU - Lawyer, P. G.

AU - Warburg, A.

PY - 1993

Y1 - 1993

N2 - The sand fly Lutzomyia longipalpis is the vector of Leishmania donovani chagasi in Latin America. An analysis of genetic variability at 27 enzyme coding loci among three laboratory populations of Lu. longipalpis revealed substantial genetic polymorphism. Levels of genetic distance between all pairwise comparisons of colonies were very high, and consistent with those previously reported among separate species in the genus Lutzomyia. Between 7% and 22% of the loci studied were diagnostic for any two of the colony populations. Experimental hybridization between colonies resulted in the production of sexually sterile male progeny. Our results provide strong evidence that Lu. longipalpis exists in nature as a complex of at least three distinct species. The possible effects of colonization on the genetic makeup of laboratory populations is considered in extending our results to natural populations.

AB - The sand fly Lutzomyia longipalpis is the vector of Leishmania donovani chagasi in Latin America. An analysis of genetic variability at 27 enzyme coding loci among three laboratory populations of Lu. longipalpis revealed substantial genetic polymorphism. Levels of genetic distance between all pairwise comparisons of colonies were very high, and consistent with those previously reported among separate species in the genus Lutzomyia. Between 7% and 22% of the loci studied were diagnostic for any two of the colony populations. Experimental hybridization between colonies resulted in the production of sexually sterile male progeny. Our results provide strong evidence that Lu. longipalpis exists in nature as a complex of at least three distinct species. The possible effects of colonization on the genetic makeup of laboratory populations is considered in extending our results to natural populations.

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JF - American Journal of Tropical Medicine and Hygiene

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Lutzomyia longipalpis is a species complex: Genetic divergence and interspecific hybrid sterility among three populations

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