Lymphoid Leukemias

Moshe E. Gatt, Shai Izraeli

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are the two most common leukemias of the immune system. Each of these diseases is characterized by diverse somatic driving aberrations of significant prognostic significance, and these are used for risk stratification and adjustment of therapy. Recent advances in the science of immunology have resulted in dramatic development of new and effective therapies for patients with these malignancies.

Original languageAmerican English
Title of host publicationClinical Immunology
Subtitle of host publicationPrinciples and Practice
PublisherElsevier
Pages1049-1063.e1
ISBN (Electronic)9780702068966
ISBN (Print)9780702070396
DOIs
StatePublished - 1 Jan 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Ltd. All rights reserved.

Keywords

  • Acute lymphoblastic leukemia
  • B-cell receptor signaling
  • Chronic lymphocytic leukemia
  • Clonal diversity
  • Immunotherapy

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