Lymphoid Leukemias

Sarah Elitzur, Shai Izraeli, Dina Ben-Yehuda, Moshe E. Gatt

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are the two most common leukemias of the immune system. Each of these diseases is characterized by diverse somatic driving aberrations of significant prognostic significance, and these are used for risk stratification and adjustment of therapy. Recent advances in the science of immunology have resulted in dramatic development of new and effective therapies for patients with these malignancies.

Original languageEnglish
Title of host publicationClinical Immunology
Subtitle of host publicationPrinciples and Practice, Sixth Edition
PublisherElsevier
Pages984-999
Number of pages16
ISBN (Electronic)9780702081651
ISBN (Print)9780702081668
DOIs
StatePublished - 1 Jan 2022
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Ltd. All rights reserved.

Keywords

  • Acute lymphoblastic leukemia
  • B-cell receptor signaling
  • chronic lymphocytic leukemia
  • clonal diversity
  • immunotherapy

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