TY - JOUR
T1 - Macroion-Induced Compositional Instability of Binary Fluid Membranes
AU - May, Sylvio
AU - Harries, Daniel
AU - Ben-Shaul, Avinoam
PY - 2002
Y1 - 2002
N2 - Macroion adsorption on a mixed, fluid, lipid membrane containing oppositely charged lipids induces local changes in lipid composition at the interaction zones, and gradients at their boundaries. Including these effects in the free energy of the macroion-dressed membrane we derive its spinodal equation, and show that nonideal lipid mixing can lead to (lipid-mediated) attraction between macroions and lateral phase separation in the composite membrane. The critical nonideality for this transition is substantially smaller than that of the bare lipid membrane, decreasing with macroion size and charge. That is, the lipid membrane is destabilized by macroion adsorption.
AB - Macroion adsorption on a mixed, fluid, lipid membrane containing oppositely charged lipids induces local changes in lipid composition at the interaction zones, and gradients at their boundaries. Including these effects in the free energy of the macroion-dressed membrane we derive its spinodal equation, and show that nonideal lipid mixing can lead to (lipid-mediated) attraction between macroions and lateral phase separation in the composite membrane. The critical nonideality for this transition is substantially smaller than that of the bare lipid membrane, decreasing with macroion size and charge. That is, the lipid membrane is destabilized by macroion adsorption.
UR - http://www.scopus.com/inward/record.url?scp=18744365208&partnerID=8YFLogxK
U2 - 10.1103/PhysRevLett.89.268102
DO - 10.1103/PhysRevLett.89.268102
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C2 - 12484858
AN - SCOPUS:18744365208
SN - 0031-9007
VL - 89
JO - Physical Review Letters
JF - Physical Review Letters
IS - 26
ER -