Abstract
Taking DNA analysis for a spin: Amplified detection of viral DNA and single-base mutations in nucleic acids is accomplished by the thermally cycled incorporation of biotin labels into DNA replica associated with magnetic particles, by the electrocatalyzed biochemiluminescence transduction of the DNA recognition events, and by the rotation of the magnetic particles on electrode surfaces (see schematic representation).
Original language | English |
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Pages (from-to) | 2372-2376 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 42 |
Issue number | 21 |
DOIs | |
State | Published - 30 May 2003 |
Keywords
- Biosensors
- Chemiluminescence
- DNA
- Magnetic particles