Many ligands and states of bitter taste GPCRs

Evgenii Ziaikin; Nitsan Dallal; Masha Y. Niv

doi:10.1038/s41594-026-01790-y

Many ligands and states of bitter taste GPCRs

Evgenii Ziaikin
, Nitsan Dallal
, Masha Y. Niv^*

^*Corresponding author for this work

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Comment/debate

Abstract

Bitter taste receptors are a subtype of G-protein receptors that are activated by a variety of ligands, leading to bitter taste sensation. Two studies now report new details of ligand binding by the human TAS2R43, TAS2R14 and TAS2R46 receptors.

Original language	English
Pages (from-to)	555-557
Number of pages	3
Journal	Nature Structural and Molecular Biology
Volume	33
Issue number	4
DOIs	https://doi.org/10.1038/s41594-026-01790-y
State	Published - Apr 2026

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Publisher Copyright:
© Springer Nature America, Inc. 2026.

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title = "Many ligands and states of bitter taste GPCRs",

abstract = "Bitter taste receptors are a subtype of G-protein receptors that are activated by a variety of ligands, leading to bitter taste sensation. Two studies now report new details of ligand binding by the human TAS2R43, TAS2R14 and TAS2R46 receptors.",

author = "Evgenii Ziaikin and Nitsan Dallal and Niv, \{Masha Y.\}",

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AU - Niv, Masha Y.

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Many ligands and states of bitter taste GPCRs

Abstract

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