TY - JOUR
T1 - Matching the Heart to Heat-Induced Circulatory Load
T2 - Heat-Acclimatory Responses
AU - Horowitz, Michal
PY - 2003/12
Y1 - 2003/12
N2 - Heat acclimation enhances cardiac efficiency by increasing stroke volume and decreasing heart rate. These adaptations involve biochemical changes in the contractile apparatus, switched on by altered expression of genes coding contractile and calcium-regulatory proteins and partially mediated by persistent low thyroxine. Heat acclimation also produces cross-tolerance to oxygen deprivation, thus reinforcing cardiac adaptation to oxygen demand/supply mismatching via energy-sparing pathways.
AB - Heat acclimation enhances cardiac efficiency by increasing stroke volume and decreasing heart rate. These adaptations involve biochemical changes in the contractile apparatus, switched on by altered expression of genes coding contractile and calcium-regulatory proteins and partially mediated by persistent low thyroxine. Heat acclimation also produces cross-tolerance to oxygen deprivation, thus reinforcing cardiac adaptation to oxygen demand/supply mismatching via energy-sparing pathways.
UR - http://www.scopus.com/inward/record.url?scp=0345731130&partnerID=8YFLogxK
U2 - 10.1152/nips.01453.2003
DO - 10.1152/nips.01453.2003
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C2 - 14614152
AN - SCOPUS:0345731130
SN - 0886-1714
VL - 18
SP - 215
EP - 221
JO - News in Physiological Sciences
JF - News in Physiological Sciences
IS - 6
ER -