Matching the Heart to Heat-Induced Circulatory Load: Heat-Acclimatory Responses

Michal Horowitz*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations

Abstract

Heat acclimation enhances cardiac efficiency by increasing stroke volume and decreasing heart rate. These adaptations involve biochemical changes in the contractile apparatus, switched on by altered expression of genes coding contractile and calcium-regulatory proteins and partially mediated by persistent low thyroxine. Heat acclimation also produces cross-tolerance to oxygen deprivation, thus reinforcing cardiac adaptation to oxygen demand/supply mismatching via energy-sparing pathways.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalNews in Physiological Sciences
Volume18
Issue number6
DOIs
StatePublished - Dec 2003

Fingerprint

Dive into the research topics of 'Matching the Heart to Heat-Induced Circulatory Load: Heat-Acclimatory Responses'. Together they form a unique fingerprint.

Cite this