TY - JOUR
T1 - Matrices of acidic β-sheet peptides as templates for calcium phosphate mineralization
AU - Segman-Magidovich, Shlomit
AU - Grisaru, Haviv
AU - Gitli, Tamar
AU - Levi-Kalisman, Yael
AU - Rapaport, Hanna
PY - 2008/6/4
Y1 - 2008/6/4
N2 - Early stage of calcium phosphate mineralization on designed β-sheet peptides was monitored that may serve as nucleating templates for hydroxyapatite. A solution composed of the various ions present in the blood serum, in 1.5× their physiological concentration, was selected to monitor the mineralization under conditions that may be of biological relevancy. A film of the peptide that is spread on SBF1.5 and held 18 hrs in the expanded state prior to compression, becomes less compressible. The TEM images showed structural features that are nanomeric in scale, and found that the flat calcium phosphate sheets could be a form of unchanged amorphous calcium phosphate aggregates. The 20 days mineralized peptide film shows the most prominent differences between the 20 days and 10 days spectra with an enhanced absorption at 1037 cm-1.
AB - Early stage of calcium phosphate mineralization on designed β-sheet peptides was monitored that may serve as nucleating templates for hydroxyapatite. A solution composed of the various ions present in the blood serum, in 1.5× their physiological concentration, was selected to monitor the mineralization under conditions that may be of biological relevancy. A film of the peptide that is spread on SBF1.5 and held 18 hrs in the expanded state prior to compression, becomes less compressible. The TEM images showed structural features that are nanomeric in scale, and found that the flat calcium phosphate sheets could be a form of unchanged amorphous calcium phosphate aggregates. The 20 days mineralized peptide film shows the most prominent differences between the 20 days and 10 days spectra with an enhanced absorption at 1037 cm-1.
UR - http://www.scopus.com/inward/record.url?scp=55049134411&partnerID=8YFLogxK
U2 - 10.1002/adma.200702125
DO - 10.1002/adma.200702125
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:55049134411
SN - 0935-9648
VL - 20
SP - 2156
EP - 2161
JO - Advanced Materials
JF - Advanced Materials
IS - 11
ER -