Abstract
Particles of enamel dissected from rat mandibular incisors were analyzed in order to establish the fluoride distribution in developing enamel in relation to the chemical changes occurring during the period of development. The findings indicate that fluoride concentrations decreased as the tissue mineralized. There was usually a relatively high concentration of fluoride, however, in the stage of development corresponding to the period of late formation or early maturation, when the tissue was porous. Some of the fluoride in this area appeared to be labile and might influence nearby cells, thereby affecting the tissue's development and mineralization. Such a mechanism might explain the recognized sensitivity of enamel to dental fluorosis.
| Original language | English |
|---|---|
| Pages (from-to) | 64-69 |
| Number of pages | 6 |
| Journal | Fluoride - Quarterly Reports |
| Volume | 15 |
| Issue number | 2 |
| State | Published - 1982 |
| Externally published | Yes |