Membrane conductance and action potential of a regenerating axonal tip

Hamutal Meiri; Miha E. Spira; Itzak Parnas

doi:10.1126/science.7455707

Membrane conductance and action potential of a regenerating axonal tip

Hamutal Meiri^*, Miha E. Spira, Itzak Parnas

^*Corresponding author for this work

Alexander Silberman Institute of Life Sciences

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

The electrical membrane properties of axotomized and regenerating giant axons from the nerve cord of the cockroach Periplaneta americana were studied. Immediately after axotomy there was a decrease in resting potential, input resistance, and action potential amplitude near the cut end. This decrease was followed by the disappearance of the sodium-dependent action potential; an increase in the resting membrane conductance to K⁺, Na⁺, and Ca²⁺; and the appearance of a calcium-dependent action potential.

Original language	English
Pages (from-to)	709-712
Number of pages	4
Journal	Science
Volume	211
Issue number	4483
DOIs	https://doi.org/10.1126/science.7455707
State	Published - 1981

Access to Document

10.1126/science.7455707

Cite this

@article{30a1aab997de4e71ab5fa5dee3b40e83,

title = "Membrane conductance and action potential of a regenerating axonal tip",

abstract = "The electrical membrane properties of axotomized and regenerating giant axons from the nerve cord of the cockroach Periplaneta americana were studied. Immediately after axotomy there was a decrease in resting potential, input resistance, and action potential amplitude near the cut end. This decrease was followed by the disappearance of the sodium-dependent action potential; an increase in the resting membrane conductance to K+, Na+, and Ca2+; and the appearance of a calcium-dependent action potential.",

author = "Hamutal Meiri and Spira, {Miha E.} and Itzak Parnas",

year = "1981",

doi = "10.1126/science.7455707",

language = "אנגלית",

volume = "211",

pages = "709--712",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4483",

}

TY - JOUR

T1 - Membrane conductance and action potential of a regenerating axonal tip

AU - Meiri, Hamutal

AU - Spira, Miha E.

AU - Parnas, Itzak

PY - 1981

Y1 - 1981

N2 - The electrical membrane properties of axotomized and regenerating giant axons from the nerve cord of the cockroach Periplaneta americana were studied. Immediately after axotomy there was a decrease in resting potential, input resistance, and action potential amplitude near the cut end. This decrease was followed by the disappearance of the sodium-dependent action potential; an increase in the resting membrane conductance to K+, Na+, and Ca2+; and the appearance of a calcium-dependent action potential.

AB - The electrical membrane properties of axotomized and regenerating giant axons from the nerve cord of the cockroach Periplaneta americana were studied. Immediately after axotomy there was a decrease in resting potential, input resistance, and action potential amplitude near the cut end. This decrease was followed by the disappearance of the sodium-dependent action potential; an increase in the resting membrane conductance to K+, Na+, and Ca2+; and the appearance of a calcium-dependent action potential.

UR - http://www.scopus.com/inward/record.url?scp=0019414705&partnerID=8YFLogxK

U2 - 10.1126/science.7455707

DO - 10.1126/science.7455707

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0019414705

SN - 0036-8075

VL - 211

SP - 709

EP - 712

JO - Science

JF - Science

IS - 4483

ER -

Membrane conductance and action potential of a regenerating axonal tip

Abstract

Access to Document

Other files and links

Fingerprint

Cite this