TY - JOUR
T1 - Membrane differentiation in rat dorsal root ganglia and possible consequences for back pain
AU - Devor, Marshall
AU - Obermayer, Malu
PY - 1984/10/26
Y1 - 1984/10/26
N2 - The ferric ion-ferrocyanide staining procedure (Quick and Waxman, J. Neurol. Sci., 31 (1977) 1-11), believed to label selectively membrane regions with high sodium-channel content and hence elevated electrical excitability, was used to stain lower lumbar dorsal root ganglion (DRG) neurons in adult rats. In many such cells, including both large type A neurons and small type B neurons, the initial segment of the stem axon and a variable portion of the adjacent soma surface stained heavily. It is suggested that this membrane specialization represents a zone of elevated excitability which may contribute to ectopic impulse generation in DRGs.
AB - The ferric ion-ferrocyanide staining procedure (Quick and Waxman, J. Neurol. Sci., 31 (1977) 1-11), believed to label selectively membrane regions with high sodium-channel content and hence elevated electrical excitability, was used to stain lower lumbar dorsal root ganglion (DRG) neurons in adult rats. In many such cells, including both large type A neurons and small type B neurons, the initial segment of the stem axon and a variable portion of the adjacent soma surface stained heavily. It is suggested that this membrane specialization represents a zone of elevated excitability which may contribute to ectopic impulse generation in DRGs.
KW - dorsal root ganglion
KW - membrane differentiation
KW - nerve
KW - pain
UR - http://www.scopus.com/inward/record.url?scp=0021691237&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(84)90400-2
DO - 10.1016/0304-3940(84)90400-2
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C2 - 6084206
AN - SCOPUS:0021691237
SN - 0304-3940
VL - 51
SP - 341
EP - 346
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 3
ER -