Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway

Keyphrases

• Nucleotide Exchange Factor 100%
• Membrane Targeting 100%
• RAS Pathway 100%
• Farnesylation 100%
• C-terminal Region 66%
• Grb2 66%
• Myristoylation 66%
• Tyrosine Phosphorylation 33%
• Inhibitory Effect 33%
• Mammalian Cells 33%
• Cell Membrane 33%
• Activator protein-1 (AP-1) 33%
• Growth Hormone Receptor 33%
• Plasma Membrane 33%
• ERK1 33%
• Ras Signaling 33%
• Oncogenic Transformation 33%
• Plasma Membrane Targeting 33%
• Ion Exchanger 33%
• Yeast Plasma Membrane 33%
• Membrane Recruitment 33%
• Activated Ras 33%
• Secondary Mechanisms 33%
• SH2 Domain 33%

Biochemistry, Genetics and Molecular Biology

• Nucleotide Exchange Factor 100%
• Signal Transduction 100%
• Cell Membrane 100%
• C-Terminus 66%
• Myristoylation 66%
• Mammalian Cell 33%
• Growth Factor Receptor 33%
• Tyrosine 33%
• Autophosphorylation 33%
• Fungal Membrane 33%
• SH2 Domain 33%