Mesenchymal Stem Cells

Zulma Gazit; Gadi Pelled; Dmitriy Sheyn; Doron C. Yakubovich; Dan Gazit

doi:10.1016/B978-0-12-809880-6.00014-X

Mesenchymal Stem Cells

Zulma Gazit, Gadi Pelled, Dmitriy Sheyn, Doron C. Yakubovich, Dan Gazit

Institute of Biomedical Research at the Faculty of Dental Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

15 Scopus citations

Abstract

The authors review the current status of research on mesenchymal stem cells (MSCs), a plastic-adherent cell population that can be directed to differentiate in vitro into cells of osteogenic, chondrogenic, adipogenic, myogenic, and other lineages. Characteristics of MSCs that lend to their being used in stem cell applications are described. Various tissues containing MSCs are specified and the methods by which these cells can be isolated are explicated. The relationship between MSCs and the immune system are discussed. In addition, the authors offer a review of current knowledge of MSC exomes and their place in stem cell–driven therapy, as well as a discussion of induced pluripotent stem cell–derived MSCs.

Original language	English
Title of host publication	Principles of Regenerative Medicine
Publisher	Elsevier
Pages	205-218
Number of pages	14
ISBN (Electronic)	9780128098806
ISBN (Print)	9780128098936
DOIs	https://doi.org/10.1016/B978-0-12-809880-6.00014-X
State	Published - 1 Jan 2018

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc. All rights reserved.

Keywords

Exosomes
Immunoisolation
iMSCs
Mesenchymal stem cells (MSCs)
MSC immunomodulation
Stemness

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10.1016/B978-0-12-809880-6.00014-X

Cite this

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AU - Pelled, Gadi

AU - Sheyn, Dmitriy

AU - Yakubovich, Doron C.

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KW - Stemness

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Mesenchymal Stem Cells

Abstract

Bibliographical note

Keywords

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