Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects

Ewa Kozela; Neta Regev-Rudzki; Guy Smagghe

doi:10.1007/978-3-031-81549-2_7

Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects

Ewa Kozela
, Neta Regev-Rudzki^*
, Guy Smagghe

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Extracellular vesicles (EVs) are membrane-enclosed nanometer-scale particles and have been discovered in nearly all kingdoms of life as a form of cellular communication across different cells and between interacting organisms. They can transport biological materials such as RNAs, proteins and metabolites. It should be noted that research on EVs has primarily focused on EV-mediated intra-organismal transport in mammals. However, the overall molecular content and functions of EVs in other kingdoms remain largely unknown. This chapter will also highlight on recent advances in EV-mediated communications in parasite–host interactions and report on the presence of EVs in insects and their potential role in systemic RNA interference (RNAi) in insects.

Original language	English
Title of host publication	RNA interference in Agriculture
Subtitle of host publication	Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses
Publisher	Springer Science+Business Media
Pages	121-144
Number of pages	24
ISBN (Electronic)	9783031815492
ISBN (Print)	9783031815485
DOIs	https://doi.org/10.1007/978-3-031-81549-2_7
State	Published - 1 Jan 2025
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2025 Springer Nature Switzerland AG.

Keywords

Cargo
Extracellular vesicles
Host
Insects
Parasites
RNAi
dsRNA

Access to Document

10.1007/978-3-031-81549-2_7

Cite this

Kozela, E., Regev-Rudzki, N., & Smagghe, G. (2025). Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects. In RNA interference in Agriculture: Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses (pp. 121-144). Springer Science+Business Media. https://doi.org/10.1007/978-3-031-81549-2_7

Kozela, Ewa ; Regev-Rudzki, Neta ; Smagghe, Guy. / Message in a Vesicle : The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects. RNA interference in Agriculture: Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses. Springer Science+Business Media, 2025. pp. 121-144

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Kozela, E, Regev-Rudzki, N & Smagghe, G 2025, Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects. in RNA interference in Agriculture: Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses. Springer Science+Business Media, pp. 121-144. https://doi.org/10.1007/978-3-031-81549-2_7

Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects. / Kozela, Ewa; Regev-Rudzki, Neta; Smagghe, Guy.
RNA interference in Agriculture: Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses. Springer Science+Business Media, 2025. p. 121-144.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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Kozela E, Regev-Rudzki N, Smagghe G. Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects. In RNA interference in Agriculture: Basic Science to Applications: From Bioinformatics and Laboratory Assays Over Regulatory Issues to Field Uses. Springer Science+Business Media. 2025. p. 121-144 doi: 10.1007/978-3-031-81549-2_7

Message in a Vesicle: The Role of Extracellular Vesicle Cargo in Parasite–Host Inter-Kingdom Communication and Spread of Systemic RNAi in Insects

Abstract

Bibliographical note

Keywords

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