Abstract
Fusobacterium nucleatum is present in colon cancers where it was shown to generate a proinflammatory microenvironment that supports colorectal neoplasia progression. Remarkably, alongside with proinflammatory stimulation, fusobacteria also inhibit cytotoxicity of immune cells. Thus, it appears as if tumors exploit fusobacteria to generate a favorable proinflammatory and anti-cytotoxic microenvironment.
| Original language | English |
|---|---|
| Pages (from-to) | 1-3 |
| Number of pages | 3 |
| Journal | OncoImmunology |
| Volume | 4 |
| Issue number | 9 |
| DOIs | |
| State | Published - 1 Jan 2015 |
Bibliographical note
Publisher Copyright:© 2015 Taylor & Francis Group, LLC.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Colon adenocarcinoma
- Fusobacteria
- NK cells
- Tumor immunity
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