Abstract
An approach to study the real-time dynamics of single molecules using capacitance measurements was described. It was shown that the method is based on a nonparallel-plate microcapacitor, which has a tapered-gap geometry. It was found that the detection scheme also enables the distinction between particles of different dielectric constants and the exertion of dielectrophoretic forces on the particles. The results show that the approach provides a means for studying various aspects of single-particle dynamics at high resolution, in real time, and under conditions compatible with biological systems.
Original language | English |
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Pages (from-to) | 4277-4279 |
Number of pages | 3 |
Journal | Applied Physics Letters |
Volume | 84 |
Issue number | 21 |
DOIs | |
State | Published - 24 May 2004 |