Micro-RNAs and breast cancer

John Le Quesne; Carlos Caldas

doi:10.1016/j.molonc.2010.04.009

Micro-RNAs and breast cancer

John Le Quesne
, Carlos Caldas^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

105 Scopus citations

Abstract

Micro-RNAs (miRs) are a recently described class of genes, encoding small non-coding RNA molecules, which primarily act by down-regulating the translation of target mRNAs. miRs are involved in a range of normal physiological processes, notably differentiation and cell type determination. It has become apparent that they are also key factors in cancer, playing both oncogenic and tumour-suppressing roles. We discuss here what is known of miR biology in the normal breast, and of their emerging roles in breast cancer.

Original language	English
Pages (from-to)	230-241
Number of pages	12
Journal	Molecular Oncology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.molonc.2010.04.009
State	Published - Jun 2010
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Breast cancer, oncogenes
Micro-RNA
Tumor suppressors

Access to Document

10.1016/j.molonc.2010.04.009

Cite this

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KW - Micro-RNA

KW - Tumor suppressors

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Micro-RNAs and breast cancer

Abstract

UN SDGs

Keywords

Access to Document

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