Micrornas: New players in multiple myeloma

Flavia Pichiorri*, Luciana De Luca, Rami I. Aqeilan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.

Original languageAmerican English
Article numberArticle 22
JournalFrontiers in Genetics
Volume2
Issue numberMAY
DOIs
StatePublished - 2011

Keywords

  • MDM2
  • MiRNAs
  • Microarray
  • Multiple myeloma
  • P53
  • Profiling

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