Abstract
MicroRNAs (miRNAs) are short non-coding RNAs that play critical roles in numerous cellular processes through post-transcriptional regulating functions. The aberrant role of miRNAs has been reported in a number of hematopoietic malignancies including multiple myeloma (MM). In this review we summarize the current knowledge on roles of miRNAs in the pathogenesis of MM.
Original language | English |
---|---|
Article number | Article 22 |
Journal | Frontiers in Genetics |
Volume | 2 |
Issue number | MAY |
DOIs | |
State | Published - 2011 |
Keywords
- MDM2
- MiRNAs
- Microarray
- Multiple myeloma
- P53
- Profiling