Mineralization of Trophoblast Basement Membrane

Ilana Ariel; Karen Meir

doi:10.1007/978-3-319-97214-5_19

Mineralization of Trophoblast Basement Membrane

Ilana Ariel^*
, Karen Meir

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

6 Scopus citations

Abstract

Sedimentation of minerals, specifically calcium phosphate and iron as haemosiderin, along the basement membrane of the chorionic villus results in blue-purple discolouration of the trophoblast basement membrane (TBM). This phenomenon may be seen in fibrotic avascular villi in livebirths and is prominent in stillbirths. It is also observed in villi with normal-looking vasculature, especially in aneuploidy, malformation syndromes, polyhydramnios, fetal hydrops and more. Genetic disorders of calcium and iron metabolism, such as Bartter syndrome and thalassaemia, frequently exhibit TBM mineralization.

Original language	English
Title of host publication	Pathology of the Placenta
Subtitle of host publication	A Practical Guide
Publisher	Springer International Publishing
Pages	143-146
Number of pages	4
ISBN (Electronic)	9783319972145
ISBN (Print)	9783319972138
DOIs	https://doi.org/10.1007/978-3-319-97214-5_19
State	Published - 1 Jan 2018
Externally published	Yes

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2019.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Calcification
Haemosiderosis
Mineralization
Trophoblast basement membrane

Access to Document

10.1007/978-3-319-97214-5_19

Cite this

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abstract = "Sedimentation of minerals, specifically calcium phosphate and iron as haemosiderin, along the basement membrane of the chorionic villus results in blue-purple discolouration of the trophoblast basement membrane (TBM). This phenomenon may be seen in fibrotic avascular villi in livebirths and is prominent in stillbirths. It is also observed in villi with normal-looking vasculature, especially in aneuploidy, malformation syndromes, polyhydramnios, fetal hydrops and more. Genetic disorders of calcium and iron metabolism, such as Bartter syndrome and thalassaemia, frequently exhibit TBM mineralization.",

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Mineralization of Trophoblast Basement Membrane

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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