Minor salivary glands: Clinical, histological and immunohistochemical features of common and less common pathologies

Doron J. Aframian; Naama Keshet; Chen Nadler; Yehuda Zadik; Marilena Vered

doi:10.1016/j.acthis.2019.151451

Minor salivary glands: Clinical, histological and immunohistochemical features of common and less common pathologies

Doron J. Aframian^*, Naama Keshet, Chen Nadler, Yehuda Zadik, Marilena Vered

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Abstract

Hundreds of minor salivary glands (MiSGs) are scattered in the oral cavity located at the submucosa layer. Beside their role in the oral cavity lubrication and immunity defence system, MiSGs are beneficial tissue source for diagnosing oral and non-oral related diseases. The advantage of MiSGs as a diagnostic tool reside on their fairly simple excisional procedure on one hand and negligible impact of the normal secretion capability of the salivary gland system on the other hand. The review focuses on pathologies related to developmental, reactive, metabolic, inflammatory and immunologic conditions, Iatrogenic causes and other undefined causes.

Original language	English
Article number	151451
Journal	Acta Histochemica
Volume	121
Issue number	8
DOIs	https://doi.org/10.1016/j.acthis.2019.151451
State	Published - Nov 2019

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© 2019 Elsevier GmbH

Keywords

Minor Salivary glands

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10.1016/j.acthis.2019.151451

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abstract = "Hundreds of minor salivary glands (MiSGs) are scattered in the oral cavity located at the submucosa layer. Beside their role in the oral cavity lubrication and immunity defence system, MiSGs are beneficial tissue source for diagnosing oral and non-oral related diseases. The advantage of MiSGs as a diagnostic tool reside on their fairly simple excisional procedure on one hand and negligible impact of the normal secretion capability of the salivary gland system on the other hand. The review focuses on pathologies related to developmental, reactive, metabolic, inflammatory and immunologic conditions, Iatrogenic causes and other undefined causes.",

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AU - Keshet, Naama

AU - Nadler, Chen

AU - Zadik, Yehuda

AU - Vered, Marilena

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AB - Hundreds of minor salivary glands (MiSGs) are scattered in the oral cavity located at the submucosa layer. Beside their role in the oral cavity lubrication and immunity defence system, MiSGs are beneficial tissue source for diagnosing oral and non-oral related diseases. The advantage of MiSGs as a diagnostic tool reside on their fairly simple excisional procedure on one hand and negligible impact of the normal secretion capability of the salivary gland system on the other hand. The review focuses on pathologies related to developmental, reactive, metabolic, inflammatory and immunologic conditions, Iatrogenic causes and other undefined causes.

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Minor salivary glands: Clinical, histological and immunohistochemical features of common and less common pathologies

Abstract

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