Abstract
Summary: The miRror application provides insights on microRNA (miRNA) regulation. It is based on the notion of a combinatorial regulation by an ensemble of miRNAs or genes. miRror integrates predictions from a dozen of miRNA resources that are based on complementary algorithms into a unified statistical framework. For miRNAs set as input, the online tool provides a ranked list of targets, based on set of resources selected by the user, according to their significance of being coordinately regulated. Symmetrically, a set of genes can be used as input to suggest a set of miRNAs. The user can restrict the analysis for the preferred tissue or cell line. miRror is suitable for analyzing results from miRNAs profiling, proteomics and gene expression arrays.
| Original language | English |
|---|---|
| Article number | btq298 |
| Pages (from-to) | 1920-1921 |
| Number of pages | 2 |
| Journal | Bioinformatics |
| Volume | 26 |
| Issue number | 15 |
| DOIs | |
| State | Published - 6 Jun 2010 |
Bibliographical note
Funding Information:Funding: EU Framework VII Prospects consortium; grant from ISF 592/07; grant from BSF 2007219; fellowship from the SCCB, the Sudarsky Center for Computational Biology (to G.N.).