Misaminoacylation and tRNA-dependent transamidation in Streptomyces coelicolor A3(2)

Astrid Schön*, J. Stefan Rokem

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Streptomyces coelicolor was found to be devoid of glutaminyl-tRNA synthetase. In this bacterium, tRNAGln is aminoacylated by glutamyl-tRNA synthetase to yield glutamyl-tRNAGln, followed by correction to glutaminyl-tRNAGln by a tRNA-dependent amidotransferase.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalFEMS Microbiology Letters
Volume92
Issue number1
DOIs
StatePublished - 1 Apr 1992
Externally publishedYes

Keywords

  • Amidotransferase
  • Glutamyl-tRNA synthetase
  • Mischarging
  • Protein synthesis
  • Streptomyces
  • tRNA

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