Mitochondrial activity is required for the expression of IME1, a regulator of meiosis in yeast

Millet Treinin*, Giora Simchen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Sporulation in the yeast Saccharomyces cerevisiae occurs in diploid cells following starvation for glucose and nitrogen sources. A key gene in the regulation of the meiotic process is IME1. A well-documented fact is that respiration is necessary for sporulation. We now show that respiration is necessary for the expression of IME1. We suggest that glucose repression of meiosis is transduced through its effect on respiration, in a pathway separate from that of adenylyl cyclase.

Original languageAmerican English
Pages (from-to)223-227
Number of pages5
JournalCurrent Genetics
Volume23
Issue number3
DOIs
StatePublished - Mar 1993

Keywords

  • Meiosis
  • Mitochondria
  • Respiration
  • Sporulation

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