Mo(CO) 6-mediated intramolecular pauson-Khand reaction of substituted Diethyl 3-Allyloxy-1-Propynylphosphonates

Dorit Moradov*, Abed Al Aziz Al Quntar, Manar Youssef, Reem Smoum, Abraham Rubinstein, Morris Srebnik

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Cyclisation of diethyl 3-allyloxy-1-propynylphosphonates with Mo(CO) 6 under PK conditions to give 3-substituted-5-oxo-3,5,6,6a- tetrahydro-1H-cyclopenta[c]furan-4-ylphosphonate, 2a-h,in45-88% isolated yields was done. The R groups are always syn with H b (where applicable). The stereochemistry was determined via both NMR and crystal X-ray analysis.

Original languageEnglish
Pages (from-to)1029-1033
Number of pages5
JournalJournal of Organic Chemistry
Volume74
Issue number3
DOIs
StatePublished - 6 Feb 2009

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